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Summary
Shigella and Salmonella infections were common in newly arrived monkeys, with many bacterial strains showing antibiotic resistance. Further study revealed no seasonal patterns in these infections within the primate colony.
Area of Science:
- Veterinary Microbiology
- Primate Health
- Infectious Diseases
Background:
- Primate research facilities require rigorous health monitoring of animals.
- Shigella and Salmonella are significant bacterial pathogens affecting non-human primates.
- Antibiotic resistance in zoonotic bacteria poses a public health concern.
Purpose of the Study:
- To determine the prevalence of Shigella and Salmonella infections in imported primates.
- To characterize the antibiotic resistance patterns of isolated bacterial strains.
- To investigate epidemiological factors influencing infection rates in a primate colony.
Main Methods:
- Screening of 6,646 imported monkeys from 10 species for Shigella and Salmonella.
- Isolation and identification of bacterial pathogens.
- Antimicrobial susceptibility testing of bacterial isolates.
- Epidemiological analysis of infection data over a three-year period.
Main Results:
- 12% of incoming monkeys were infected with Shigella, predominantly S. flexneri 4.
- Salmonella infection incidence declined from 12% to 3% during the study.
- No seasonal variation in Shigella or Salmonella occurrence was observed in colony animals.
- A high prevalence of resistance to chloramphenicol, dihydrostreptomycin, and tetracycline was noted in isolates.
Conclusions:
- Imported primates frequently carry Shigella and Salmonella, necessitating quarantine protocols.
- The emergence and spread of antibiotic-resistant strains are significant concerns.
- Drug-resistance factors may play a role in the epidemiology of these infections in primate populations.