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Giant atrial myxoma.

Nicola Mumoli1, Aldo Fici2, Lucia Colavolpe2

  • 1Department of Cardiovascular Medicine, Ospedale Di Circolo, Via Arnaldo da Brescia, 1, 21052, Busto Arsizio, VA, Italy. nicola.mumoli@asst-valleolona.it.

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|March 10, 2026
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A giant cardiac myxoma in the left atrium caused severe symptoms by prolapsing through the mitral valve. Surgical removal of this common primary cardiac tumor led to full recovery.

Keywords:
Heart failureLeft atriumMyxoma

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Area of Science:

  • Cardiology
  • Oncology
  • Medical Imaging

Background:

  • Cardiac myxomas are the most common primary cardiac tumors, often originating in the left atrium.
  • While benign, they can cause significant hemodynamic compromise, mimicking valvular disease or heart failure.
  • Giant, mobile myxomas pose a risk of severe complications.

Purpose of the Study:

  • To illustrate the echocardiographic findings of a giant left atrial myxoma.
  • To describe the functional consequences and hemodynamic effects of such a mass.
  • To highlight diagnostic and management considerations for atrial myxomas.

Main Methods:

  • A pictorial essay format was used.
  • Transthoracic echocardiography was performed to visualize the cardiac mass.
  • Clinical presentation, echocardiographic images, and surgical outcomes were analyzed.

Main Results:

  • Echocardiography revealed a large, pedunculated left atrial mass attached to the interatrial septum.
  • The myxoma dynamically prolapsed through the mitral valve during diastole, causing obstruction and severe mitral regurgitation.
  • Surgical excision confirmed the diagnosis and resulted in complete clinical recovery.

Conclusions:

  • Giant left atrial myxomas can present with significant symptoms due to valvular obstruction.
  • Echocardiography is crucial for diagnosing cardiac myxomas and assessing their hemodynamic impact.
  • Prompt surgical intervention is effective for treating symptomatic atrial myxomas.