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Pathology in motion: Automation from specimen to report.

Vincenzo L'Imperio1, Angelo Paolo Dei Tos2, Maurizio Carbone1

  • 1Department of Medicine and Surgery, Pathology, IRCCS Fondazione San Gerardo dei Tintori, University of Milano-Bicocca, Italy.

Critical Reviews in Oncology/Hematology
|March 10, 2026
PubMed
Summary
This summary is machine-generated.

Laboratory automation enhances pathology workflow efficiency and reliability. Automating tasks like processing, embedding, and archiving significantly reduces manual labor and errors, improving diagnostic safety and staff focus.

Keywords:
AutomationCuttingDigital pathologyEmbeddingPathology workflow

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Area of Science:

  • Medical Laboratory Science
  • Pathology Workflow Optimization

Background:

  • Pathology labs face increasing diagnostic demand, complexity, and staffing shortages.
  • Current manual workflows are inefficient, error-prone, and contribute to staff burnout.

Purpose of the Study:

  • To review automation solutions for key pathology workflow phases.
  • To compare automation efficiency and accuracy against manual methods.

Main Methods:

  • Review of current automation technologies for grossing, labeling, processing, embedding, microtomy, and archiving.
  • Comparative analysis of automated vs. manual workflow data for efficiency, accuracy, and traceability.

Main Results:

  • Automation improves efficiency and reliability across multiple pathology stages.
  • Advanced processing systems offer faster turnaround and better tissue preservation.
  • Automated embedding, microtomy, and archiving significantly reduce manual handling time and improve sample tracking.

Conclusions:

  • Automation enhances standardization, efficiency, and diagnostic safety in pathology.
  • High implementation costs and infrastructure demands are current barriers.
  • Automation is crucial for building resilient and future-ready pathology services.