Related Experiment Video
Updated: Mar 12, 2026
Short Session High Intensity Interval Training and Treadmill Assessment in Aged Mice
Published on: February 2, 2019
The Effects of Time-Restricted Feeding and Exercise on Cardiometabolic Health in Sedentary Older Adults: A Randomized
Linyu Peng1,2, Lidan Chen1, Jingbo Xia1
1Guangdong Provincial Key Laboratory of Physical Activity and Health Promotion, Guangzhou Sport University, Guangzhou, CHINA.
Purpose:
Exploring preferable lifestyle habits (diet and/or exercise) is essential in improving cardiometabolic health among older adults, who represent the most sedentary than other age populations and generally suffer from cardiometabolic problems. This study aimed to determine the effects of long-term time-restricted feeding (TRF), exercise training, and their combination on comprehensive measures of cardiovascular functions and multiple auxiliary indicators, and to simultaneously evaluate side effects and adherence.
Methods:
Fifty-six sedentary participants (age: 57.6 ± 2.2) were randomly assigned to control (CON; n = 14), exercise (EX; n = 14), TRF (n = 14), and a combinational intervention (EX+TRF; n = 14) group. Participants in each group were instructed to follow their assigned TRF and/or exercise protocol throughout an 8-wk period. The primary outcomes were changes in cardiovascular functions. Secondary outcomes included changes in body composition, metabolic parameters, circulating biomarkers, eating habits, and nutrient intake.
Results:
After 8 wks, EX (n = 11), TRF (n = 11), and EX+TRF (n = 14) produced significant increase in heart rate variability compared with CON (n = 11) ( P < 0.05); EX and EX+TRF also significantly improved flow-mediated dilation ( P < 0.05). TRF and EX+TRF significantly induced reductions in body fat percentage, lean mass, and total calorie consumption compared with CON ( P < 0.05); EX even induced significant increases in inflammatory biomarkers ( P < 0.05). Three interventions potentially caused adverse events but with no obvious difference; neither TRF nor EX produced superior adherence than the other, but there was lower compliance when counseling them both.
Conclusions:
Sedentary older adults could achieve cardiovascular health benefits by choosing either TRF or exercise lifestyle, with no obvious difference in adverse events and adherence.
More Related Videos
12:59Improving Strength, Power, Muscle Aerobic Capacity, and Glucose Tolerance through Short-term Progressive Strength Training Among Elderly People
Published on: July 5, 2017
06:28A Chronic High-Intensity Interval Training and Diet-Induced Obesity Model to Maximize Exercise Effort and Induce Physiologic Changes in Rats
Published on: April 28, 2023
Related Concept Videos
01:20Exercise and Cardiovascular Response
Light to moderate physical activity initiates a series of interconnected responses in the body. The heart rate modestly increases in anticipation of the workout, followed by widespread vasodilation as oxygen consumption by skeletal muscles increases. This results in decreased peripheral resistance, increased capillary blood flow, and accelerated...
01:17Exercise and Cardiac Output
Sustained exercise increases the muscles' oxygen demand, which can be...
01:24Metabolic States of the Body: Fasting and Starvation