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Orbital MRI for thyroid eye disease activity staging: a systematic review and meta-analysis

Shuyi Liu1, Chuang Sun2, Shuxin Liu1

  • 1Department of Ophthalmology, The Second Hospital of Dalian Medical University, Dalian, Liaoning Province, 116027, China.

BMC Ophthalmology
|March 11, 2026
PubMed
Abstract

No abstract available in PubMed .

Keywords:
Magnetic resonance imagingMeta-analysisSystematic reviewThyroid eye disease

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Graves' disease is an autoimmune disorder that causes hyperthyroidism, or overactivity of the thyroid gland. It results from autoantibodies called thyroid-stimulating immunoglobulins (TSIs), which bind to thyroid-stimulating hormone (TSH) receptors, leading to overstimulation of hormone production and a hypermetabolic state.EtiologyAlthough considered idiopathic, Graves’ disease has well-established contributing factors. There is a strong genetic component, with increased prevalence in...
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Graves’ disease is an autoimmune disorder characterized by the production of thyroid-stimulating immunoglobulins (TSI) that activate TSH receptors, leading to excessive synthesis and release of thyroid hormones (T3 and T4) and resulting in hyperthyroidism.Among all causes of hyperthyroidism, Graves’ disease is the most common and can happen at any age, though it is more frequent in women. It produces a hypermetabolic state with features such as weight loss, tachycardia, tremor, and heat...

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