Complexity and psychopathology: from mechanistic science to a physical understanding of the mental conditions based...

The Traditional Scientific Method (TSM), rooted in the Cartesian-Mechanistic Paradigm, is insufficient for the comprehensive study of the human mind and suffering, which are complex phenomena. Thus, psychiatry can pathologize many vital critical processes and neurodivergences when it simplifies subjectivity and diversity through its nosological models. This essay advocates for a shift towards the Complexity Paradigm (CP)to achieve a psychopathology more adequate to human singularity. The CP posits that life and mind are emergent dissipative phenomena arising from the synergy between chaos and order, that enables systems to adapt through self-organization while maintaining their internal stability. Therefore, organic complexity appears to decrease with age and pathologies. We explore Non-Extensive Statistical Mechanics (q-Statistics, qS), proposed by Tsallis to describe neural complexity from EEG signal through the scalar parameter q. We've demonstrated that qS, by a q-exponential function, models the EEG non-linear behavior indicating its power for quantify the brain complexity, and also to describe modulation of the complexity by ageing or neurodivergence (attention deficit/hyperactivity condition in children) in the brain as a whole, and by different functional brain states (as in oddball attention paradigm or listening a preferred piece of music) in different brain regions. We hypothesize that neural complexity could be reduced in pathological mental conditions, but not in neurodivergence, neither in mental suffering that are critical processes of transformation. Assessing neural complexity as a property of the brain through q-statistics may be a method to a more comprehensive and precise psychiatry.