Jove
Visualize
Contact Us

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Design and Development of Novel Airway Device for Transoral Respiratory Monitoring During Sedation.

The Laryngoscope·2026
Same author

VGLL3-Rearranged Spindle Cell Rhabdomyoblastic Tumor: A Clinicopathologic and Molecular Genetic Study of 18 Cases With Consistently Indolent Behavior.

Modern pathology : an official journal of the United States and Canadian Academy of Pathology, Inc·2026
Same author

Molecular Characterization of Isolated Soft Tissue Deposits in Papillary Thyroid Carcinoma.

Head & neck·2026
Same author

Pulsed ultrasound targeted to the spleen mitigates against kidney injury and promotes kidney repair.

American journal of physiology. Renal physiology·2025
Same author

<i>STRN-ALK</i> Fusion in Advanced Salivary Gland Carcinoma With Response to Anaplastic Lymphoma Kinase Inhibition: Case Report and Literature Review.

WMJ : official publication of the State Medical Society of Wisconsin·2024
Same author

Dopamine-Secreting Carotid Body Paraganglioma in a Patient With SDHB Mutation.

AACE clinical case reports·2024
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Video

Updated: Mar 12, 2026

Author Spotlight: Genetically Engineered Mouse Models and Pathological Characterization of Neurofibromatosis Type 1 Associated Tumors
08:57

Author Spotlight: Genetically Engineered Mouse Models and Pathological Characterization of Neurofibromatosis Type 1 Associated Tumors

Published on: May 17, 2024

2.7K

Case Report: Parapharyngeal Leiomyosarcoma Mimicking Neurofibroma.

Carson Brantley1, Claudia N Gutierrez2, Sara Zadeh3

  • 1College of Arts & Sciences, University of Virginia Virginia USA.

Clinical Case Reports
|March 11, 2026
PubMed
Summary

Diagnosing parapharyngeal space tumors like leiomyosarcomas and neurofibromas is difficult due to similar features. Tissue samples and immunohistochemistry are vital for accurate diagnosis and improved patient outcomes.

Keywords:
head and neck neoplasmsleiomyosarcomaneurofibromaotolaryngologyparapharyngeal space

More Related Videos

An Orthotopic Sciatic Nerve Xenograft for Neurofibromatosis Type 1 Neurofibromas
03:53

An Orthotopic Sciatic Nerve Xenograft for Neurofibromatosis Type 1 Neurofibromas

Published on: October 10, 2025

596
Surgical Treatment of an Endolymphatic Sac Tumor
04:34

Surgical Treatment of an Endolymphatic Sac Tumor

Published on: May 26, 2023

1.8K

Related Experiment Videos

Last Updated: Mar 12, 2026

Author Spotlight: Genetically Engineered Mouse Models and Pathological Characterization of Neurofibromatosis Type 1 Associated Tumors
08:57

Author Spotlight: Genetically Engineered Mouse Models and Pathological Characterization of Neurofibromatosis Type 1 Associated Tumors

Published on: May 17, 2024

2.7K
An Orthotopic Sciatic Nerve Xenograft for Neurofibromatosis Type 1 Neurofibromas
03:53

An Orthotopic Sciatic Nerve Xenograft for Neurofibromatosis Type 1 Neurofibromas

Published on: October 10, 2025

596
Surgical Treatment of an Endolymphatic Sac Tumor
04:34

Surgical Treatment of an Endolymphatic Sac Tumor

Published on: May 26, 2023

1.8K

Area of Science:

  • Oncology
  • Pathology
  • Surgical Diagnosis

Background:

  • Parapharyngeal space tumors, including leiomyosarcomas and neurofibromas, present overlapping clinical and radiographic characteristics.
  • This similarity complicates early and accurate diagnosis, potentially delaying critical treatment.

Purpose of the Study:

  • To highlight the diagnostic challenges in differentiating parapharyngeal space leiomyosarcomas from neurofibromas.
  • To emphasize the importance of tissue analysis for definitive diagnosis in non-neurocutaneous disorder patients.

Main Methods:

  • Review of clinical and radiographic presentations of parapharyngeal space tumors.
  • Discussion of the role of histopathology and immunohistochemistry in differential diagnosis.

Main Results:

  • Leiomyosarcomas and neurofibromas exhibit indistinguishable features on initial clinical and radiographic evaluation.
  • Immunohistochemistry is indispensable for distinguishing between these entities in the absence of neurocutaneous syndromes.

Conclusions:

  • Accurate diagnosis of parapharyngeal space leiomyosarcoma relies on tissue sampling and specialized testing.
  • Timely diagnosis and treatment of leiomyosarcoma are critical for enhancing patient survival and preventing disease advancement.