Related Experiment Video
Updated: Mar 12, 2026

Design of Cecal Ligation and Puncture and Intranasal Infection Dual Model of Sepsis-Induced Immunosuppression
Published on: June 15, 2019
Prolonged Emergency Department Stay, Specialist-visit Delay, and Disposition-decision Delay as System-level Risks for
Nattikarn Meelarp1, Pattraporn Singjaroen1, Sariya Suasamserm1
1Department of Emergency Medicine.
Prolonged emergency department (ED) boarding does not directly increase sepsis mortality. However, delays in specialist consultations and disposition decisions significantly elevate the risk of 30-day mortality in sepsis patients.
Area of Science:
- Emergency Medicine
- Critical Care
- Public Health
Background:
- Prolonged emergency department (ED) boarding is a critical patient safety issue.
- It can delay essential interventions for sepsis patients.
- Understanding factors contributing to mortality in sepsis is crucial for improving outcomes.
Purpose of the Study:
- To investigate the association between total ED length of stay (ED-LOS) and 30-day mortality in adult sepsis patients.
- To evaluate the impact of delays in specialist visits and disposition decisions on sepsis mortality.
Main Methods:
- Retrospective observational cohort study of adult sepsis patients in a tertiary hospital.
- Primary exposure: total ED-LOS. Secondary exposures: time to specialist visit and disposition decision.
- Outcome: 30-day in-hospital mortality. Analysis: Multivariable logistic regression.
Main Results:
- 19.5% of 868 sepsis patients died within 30 days.
- Total ED-LOS was not significantly associated with 30-day mortality.
- Delays in specialist visits (aOR: 0.84) and disposition decisions (aOR: 0.94) were independently associated with increased mortality risk.
Conclusions:
- Total ED length of stay alone is not an independent predictor of sepsis mortality.
- Delays in specialist consultations and disposition decisions represent significant patient safety targets.
- Improving care transitions is vital for enhancing sepsis patient outcomes.
Related Concept Videos
Healthcare Associated Infections II: Preventive Measures
The best practices for preventing healthcare-associated infections include hand hygiene, patient risk...
Healthcare Associated Infections I: Iatrogenic, Exogenic and Endogenic
HAIs significantly increase the cost of health care. Extended stays in healthcare institutions, increased disability, increased costs of medications, including specialized antibiotics, and prolonged recovery times add to the patient's expenses and the healthcare institution and funding bodies.
Peritoneal Dialysis II: Peritoneal Dialysis Systems and Complications
Acute Pyelonephritis II: Diagnostic Studies and Management
Pneumonia III: Complications and Assessment
Factors Affecting the Risk of Infection
The integrity and count of the white blood cells help the body resist pathogens and fight infection. When impaired, it reduces the body's resistance to pathogens. The acidic pH levels of the gastrointestinal, genitourinary tracts, and skin...