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Home-based physical activity intelligent programme for patients with lower extremity Ilizarov: a study protocol for a
Fei Lu1, Xinxin Wang2, Wenxia Wang1
1Department of Nursing, The Second Affiliated Hospital Zhejiang University School of Medicine, Hangzhou, Zhejiang, China.
BMJ Open
|March 11, 2026
Summary
This study evaluates a home-based intelligent rehabilitation program for lower extremity Ilizarov surgery patients. The program aims to improve physical activity, mental health, and quality of life post-surgery.
Area of Science:
- Orthopedic Surgery
- Rehabilitation Medicine
- Digital Health
Background:
- Lower extremity Ilizarov surgery often leads to decreased physical activity and functional decline.
- Existing rehabilitation programs lack standardization and intelligent integration for these patients.
- Home-based intelligent rehabilitation shows potential for improving postoperative outcomes.
Purpose of the Study:
- To evaluate the 6-month effects of a home-based intelligent interaction program on physical activity levels.
- To assess the program's impact on mental health, self-efficacy, and quality of life.
- To provide a standardized, intelligent rehabilitation solution for lower extremity Ilizarov surgery patients.
Main Methods:
- 166 participants undergoing lower extremity Ilizarov surgery were randomized (1:1) into HB-PAIP or control groups.
- The HB-PAIP group received a 6-month algorithm-guided home rehabilitation program via an intelligent system.
- Assessments included functional mobility (Timed Up-and-Go), walking tests, ROM, ADL, VAS, anxiety/depression scales, and serum markers.
Main Results:
- Primary outcome: functional mobility assessed by Timed Up-and-Go test.
- Secondary outcomes: 10-meter walking test, passive ankle range of motion, ADL score, VAS score.
- Mental status via Hamilton Anxiety and Depression Scales, and serum levels of hemoglobin and albumin were also measured.
Conclusions:
- The study will determine the efficacy of a novel home-based intelligent program for Ilizarov surgery recovery.
- Findings are expected to inform the development of standardized digital rehabilitation strategies.
- Improved physical activity and mental well-being are anticipated outcomes for the intervention group.

