Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Disorders of the Autonomic Nervous System01:18

Disorders of the Autonomic Nervous System

1.8K
The autonomic nervous system (ANS) is an intricate network of nerves that controls functions such as the regulation of heart rate, digestion, and blood pressure regulation. When this system malfunctions, it can lead to various disorders that affect multiple bodily functions. One common feature of many autonomic disorders is the involvement of smooth blood vessels, which play a crucial role in regulating blood flow throughout the body.
Raynaud's disease, also known as Raynaud's...
1.8K
Acute Coronary Syndrome II: Pathophysiology and Clinical Manifestations01:19

Acute Coronary Syndrome II: Pathophysiology and Clinical Manifestations

611
The pathophysiology of Acute Coronary Syndrome [ACD] involves several key processes:The main underlying cause of ACD is atherosclerosis, a chronic inflammatory disease characterized by the buildup of lipid-laden plaques within the coronary arteries.As the atherosclerotic plaque grows in the coronary artery, it may become unstable due to the formation of a lipid-rich core and a thin fibrous cap. Inflammatory cells within the plaque, such as macrophages, secrete enzymes that degrade the...
611
Coronary Artery Disease III: Clinical Manifestations01:30

Coronary Artery Disease III: Clinical Manifestations

505
Coronary Artery Disease (CAD) is a primary health risk worldwide, leading to significant morbidity and mortality. The condition arises from the buildup of atherosclerotic plaques within the coronary arteries, resulting in diminished blood supply to the heart muscle.The clinical manifestations of CAD vary widely, from asymptomatic stages to severe, life-threatening conditions. Understanding these manifestations is crucial for early diagnosis and effective management.Angina Pectoris: The Warning...
505
Psychoneuroimmunology: Cardiovascular Disease01:27

Psychoneuroimmunology: Cardiovascular Disease

645
Psychoneuroimmunology (PNI) is a multidisciplinary field that examines how psychological factors, particularly stress, interact with the immune system and impact physical health. Research in PNI has shown that chronic or traumatic stress can disrupt both the hypothalamic-pituitary-adrenal axis and the sympathetic nervous system. These disruptions contribute to serious health conditions, including cardiovascular diseases.
A key area of focus in PNI is the relationship between stress and coronary...
645
Cardiomyopathy II: Dilated Cardiomyopathy01:30

Cardiomyopathy II: Dilated Cardiomyopathy

700
Dilated cardiomyopathy, or DCM, is a progressive myocardial disorder characterized by ventricular chamber dilation and contractile dysfunction.EtiologyVarious factors can cause DCM, including hypertension and heavy alcohol intake, which contribute to the weakening and enlargement of the heart muscle. Viral infections, such as Coxsackievirus B, adenoviruses, and influenza, can lead to DCM by causing inflammation and damage to heart tissue. Certain chemotherapeutic agents, including daunorubicin,...
700
Assessment of the Cardiovascular System I: Subjective Data01:23

Assessment of the Cardiovascular System I: Subjective Data

1.0K
A thorough health history and physical assessment are essential for identifying cardiovascular disease (CVD) symptoms and distinguishing them from other health issues.
Initial Enquiry
Ask the patient about their primary concern and thoroughly explore all reported symptoms.
Medical History
Investigate past illnesses affecting the cardiovascular system, such as angina, anemia, rheumatic fever, congenital heart disease, stroke, thrombophlebitis, dysrhythmias, varicosities
Inquire about symptoms...
1.0K

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Knowledge About Psychosocial Interventions Among Individuals With Severe Mental Illness: Results of a Cross-Sectional Study.

Community mental health journal·2026
Same author

Exploring attitudes and acceptance of artificial intelligence in multiple sclerosis from the patient perspective.

PLOS digital health·2026
Same author

Intramedullary nailing versus sliding hip screw for AO/OTA 31-A2 and 31-A3 trochanteric fractures: a systematic review and meta-analysis of randomized controlled trials.

BMC musculoskeletal disorders·2026
Same author

Diagnostic and prognostic value of blood neurofilament light chain in ischemic stroke: an individual patient data meta-analysis.

Journal of neurology·2026
Same author

Etiology- and age-specific timing of death by neurologic criteria evaluation and declaration in clinical practice.

Critical care (London, England)·2026
Same author

Uterine mesenchymal neoplasm harbouring an AKAP9::BRAF fusion: identification of a novel kinase-driven molecular subset.

Virchows Archiv : an international journal of pathology·2026

Related Experiment Video

Updated: Mar 13, 2026

Autonomic Function Following Concussion in Youth Athletes: An Exploration of Heart Rate Variability Using 24-hour Recording Methodology
05:48

Autonomic Function Following Concussion in Youth Athletes: An Exploration of Heart Rate Variability Using 24-hour Recording Methodology

Published on: September 21, 2018

10.6K

Neurocardiac Autonomic Dysfunction in Patients With Post-COVID-19 Condition: A Systematic Review and Meta-Analysis.

Daniela Schoene1,2, Stefanie Deckert3, Kristian Barlinn1

  • 1Department of Neurology, Faculty of Medicine and University Hospital Carl Gustav Carus, TUD Dresden University of Technology, Dresden, Germany.

European Journal of Neurology
|March 12, 2026
PubMed
Summary

Post-COVID-19 syndrome may involve neurocardiac autonomic impairment, indicated by reduced heart rate variability (HRV). This meta-analysis found a trend toward lower HRV in patients with post-COVID condition compared to controls.

Keywords:
COVID‐19SDNNautonomic nervous systemheart rate variabilitypost‐COVID conditions

More Related Videos

Author Spotlight: A Unique Mouse Model of Asphyxia-Induced Cardiac Arrest
07:18

Author Spotlight: A Unique Mouse Model of Asphyxia-Induced Cardiac Arrest

Published on: April 14, 2023

2.4K

Related Experiment Videos

Last Updated: Mar 13, 2026

Autonomic Function Following Concussion in Youth Athletes: An Exploration of Heart Rate Variability Using 24-hour Recording Methodology
05:48

Autonomic Function Following Concussion in Youth Athletes: An Exploration of Heart Rate Variability Using 24-hour Recording Methodology

Published on: September 21, 2018

10.6K
Author Spotlight: A Unique Mouse Model of Asphyxia-Induced Cardiac Arrest
07:18

Author Spotlight: A Unique Mouse Model of Asphyxia-Induced Cardiac Arrest

Published on: April 14, 2023

2.4K

Area of Science:

  • Cardiology
  • Autonomic Neuroscience
  • Infectious Disease Epidemiology

Background:

  • SARS-CoV-2 infection is associated with neurocardiac autonomic impairment and reduced heart rate variability (HRV).
  • These autonomic dysfunctions may persist in individuals with post-COVID-19 syndrome.
  • This study synthesizes meta-analytic data on HRV in post-COVID-19 syndrome patients.

Purpose of the Study:

  • To systematically review and meta-analyze existing studies on heart rate variability (HRV) in patients diagnosed with post-COVID-19 syndrome.
  • To compare HRV parameters between individuals with post-COVID-19 syndrome and healthy controls.

Main Methods:

  • A systematic review and meta-analysis adhering to PRISMA standards.
  • Searched MEDLINE, Embase, and Web of Science for non-randomized studies comparing HRV in post-COVID-19 patients (≥3 months post-infection) with healthy controls.
  • Pooled data on standard deviation of normal-to-normal intervals (SDNN), root mean square of successive differences (rMSSD), and low-frequency to high-frequency ratio (LF/HF ratio) using a random effects model.

Main Results:

  • Included 11 studies with 1162 participants (593 post-COVID-19, 565 controls).
  • A trend towards lower HRV was observed in post-COVID-19 patients for SDNN (SMD: 0.26), rMSSD (SMD: 0.11), and LF/HF ratio (SMD: -0.271), though not statistically significant (p>0.05).
  • Significant heterogeneity (I²=78-83%) and high risk of bias (9/11 studies) were noted.

Conclusions:

  • This meta-analysis suggests a potential association between post-COVID condition and altered neurocardiac autonomic function.
  • Further high-quality research is needed to confirm these findings due to study limitations.