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In vitro Evaluation of the Digestive Tolerance of Water-Soluble Sodium β-(1→4)-Polyglucuronate
Ikuo Sato1, Eriko Kawashima2, Akira Isogai3
11 Formerly at JNC Corporation Yokohama Research Center.
Journal of Applied Glycoscience
|March 12, 2026
Abstract:
A water-soluble sodium β-(1→4)-polyglucuronate (or sodium cellouronate, Na-CUA) was prepared from regenerated cellulose by catalytic oxidation in water at pH ~10. Digestive behavior of Na-CUA was evaluated in vitro using three enzymes, α-amylase, pepsin, and pancreatin in water at 80 or 40 °C for 30 or 60 min. The results showed that 98.95 % Na-CUA remained undigested, indicating that Na-CUA is categorized as water-soluble dietary fibers.

