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Related Experiment Video

Updated: Mar 13, 2026

Optimized Management of Endovascular Treatment for Acute Ischemic Stroke

Optimized Management of Endovascular Treatment for Acute Ischemic Stroke

Published on: January 18, 2018

Visual Tools for Informed Decision-Making in Large-Core Thrombectomy for Acute Ischemic Stroke.

Amol Mehta¹, Nupur Goel², Shashvat Desai³

¹Department of Neurosurgery, Mount Sinai, New York, NY (A.M.).

Stroke (Hoboken, N.J.)

|March 12, 2026

Summary

This summary is machine-generated.

Endovascular thrombectomy (EVT) significantly improves outcomes for large-core acute ischemic stroke patients, offering substantial benefits despite increased risks. Visual aids help communicate these complex risks and benefits for better decision-making.

Keywords:

clinical decision-making endovascular procedures infarction ischemic stroke thrombectomy

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Published on: September 25, 2016

Area of Science:

Neurology
Interventional Cardiology
Public Health

Background:

Randomized trials confirm endovascular thrombectomy (EVT) benefits for large ischemic cores.
Hyperacute stroke care remains challenging, with high disability and mortality rates.
Effective risk-benefit communication is crucial, potentially aided by visual tools.

Purpose of the Study:

To pool data from large-core thrombectomy trials to quantify EVT's net benefit.
To develop visual decision aids for acute stroke care.

Main Methods:

Pooled modified Rankin Scale score data from 6 large-core thrombectomy trials.
Calculated functional independence, acceptable outcomes, and adverse events (hemorrhage, hemicraniectomy).
Quantified benefit per hundred and harm per hundred to determine net benefit; developed visual aids.

Main Results:

EVT increased functional independence (19.5% vs 7.5%) and acceptable outcomes (36.5% vs 20.0%).
EVT reduced severe disability (12.2% vs 20.6%) and mortality (31.0% vs 37.2%).
Excess harm from EVT was 3.9%, with 40/100 expected to benefit and 4/100 to experience harm.

Conclusions:

EVT offers significant benefits for large-core acute ischemic stroke.
Increased risks of hemorrhage and surgical rescue are associated with EVT.
Visual decision aids derived from pooled data facilitate informed decision-making in acute stroke.