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Ischemic Stroke ll: Pathophysiology

Ischemic Stroke ll: Pathophysiology

An ischemic stroke occurs when a cerebral blood vessel becomes obstructed, most often by a thrombus or embolus, interrupting the delivery of oxygen and glucose to brain tissue. Because neurons rely on continuous aerobic metabolism, energy failure begins within minutes of reduced perfusion. The region receiving the least blood flow becomes the infarct core, an area of irreversible cellular death. Surrounding this core lies the penumbra, a zone of hypoperfused but still viable tissue that is...

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Related Experiment Video

Updated: Jun 4, 2026

Histological Quantification of Chronic Myocardial Infarct in Rats

Histological Quantification of Chronic Myocardial Infarct in Rats

Published on: December 11, 2016

Infarct Progression Rate and Hypoperfusion Intensity Ratio: A Tautological Relationship?

Alexander Rau¹, Horst Urbach¹, Marco Reisert²

¹Department of Neuroradiology (A.R., H.U.), Medical Center-University of Freiburg, Faculty of Medicine, University of Freiburg, Germany.

Stroke (Hoboken, N.J.)

|March 12, 2026

Summary

No abstract available in PubMed .

Keywords:

brain magnetic resonance imaging patient selection perfusion thrombectomy

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