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Updated: Mar 13, 2026

Remote Limb Ischemic Preconditioning: A Neuroprotective Technique in Rodents

Remote Limb Ischemic Preconditioning: A Neuroprotective Technique in Rodents

Published on: June 2, 2015

Remote ischemic conditioning: A bibliometric analysis.

Qing Mei^1,2, Hui Shen³, Yifei Chen²

¹Department of Neurology, Xuanwu Hospital of Capital Medical University, Beijing, China.

Brain Circulation

|March 12, 2026

Summary

Remote ischemic conditioning (RIC) research is growing, with China leading publications. Future studies will focus on stroke, neuroprotection, and underlying mechanisms for this neuroregulatory technique.

Keywords:

Bibliometric analysis VOSviewer cardioprotection remote ischemic conditioning stroke

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Area of Science:

Neuroscience
Cardiology
Medical Research

Background:

Remote ischemic conditioning (RIC) is recognized as a safe and effective neuroregulatory technique.
Understanding RIC's current status and future trends requires efficient data analysis.

Purpose of the Study:

To analyze publication trends, key research areas, and global contributions in Remote Ischemic Conditioning (RIC) research.
To identify emerging hotspots and future directions in RIC studies.

Main Methods:

A comprehensive literature search was performed using the Web of Science Core Collection.
VOSviewer software was employed for bibliometric analysis and visualization of data from 1985 to 2023.

Main Results:

A total of 1,524 reviews on RIC were published between 1998 and 2023, showing a steady increase.
China led in publication volume, though citation impact varied. Key research areas include stroke, neuroprotection, and mechanism studies.

Conclusions:

RIC research publications show a consistent upward trend.
Stroke, neuroprotection, and mechanism research are identified as primary future research foci for RIC.