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Updated: Mar 13, 2026

An Oncogenic Hepatocyte-Induced Orthotopic Mouse Model of Hepatocellular Cancer Arising in the Setting of Hepatic Inflammation and Fibrosis
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FTSJ1-mediated IL1RN mRNA instability promotes inflammation-driven hepatocellular carcinoma

Shuya Jiang1, Dongyang Ding1, Yunxi Zu1

  • 1The Third Department of Hepatic Surgery, Eastern Hepatobiliary Surgery Hospital, Naval Medical University, Shanghai, China.

Journal of Gastrointestinal Oncology
|March 12, 2026
PubMed
Abstract

Keywords:
FTSJ1hepatocellular carcinoma (HCC)inflammatory microenvironmentinterleukin 1 receptor antagonist (IL1RN)messenger RNA destabilization (mRNA destabilization)

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