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Updated: May 6, 2026

Endoscopic Endonasal Trans-sphenoidal Approach: Minimally Invasive Surgery for Pituitary Adenomas
Published on: January 17, 2018
Rare Ectopic Presentation of an Intrasphenoidal Rathke's Cleft Cyst - Case Report and Literature Review
Mohammed O A Sattar1, Esther A Buckson1, Blessing Ndlovu1
1Department of Neurosurgery, Helen Joseph Hospital, Johannesburg, Gauteng, South Africa.
Abstract:
Rathke's cleft cysts (RCCs) typically present as intrasellar lesions, with exclusive sphenoid sinus involvement being exceptionally rare. We report the seventh documented case of an intrasphenoidal RCC in a 39-year-old male presenting with blurred vision and headaches. Complete resection was achieved via an endoscopic endonasal approach, and the patient remained symptom-free on follow-up. To our knowledge, this is the first report to provide a series of endoscopic images illustrating the appearance and resection technique. We review the literature on this rare entity and summarize current investigative and management paradigms.
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