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Updated: Mar 13, 2026

Tracking Bispecific Antibody-Induced T Cell Trafficking Using Luciferase-Transduced Human T Cells
Published on: May 12, 2023
Reading the "T" Leaves: Predicting Outcomes with Bispecific Antibodies in Multiple Myeloma
Rahul Banerjee1,2, Madhav V Dhodapkar1,2
1Clinical Research Division, Fred Hutchinson Cancer Center, Seattle, Washington.
Abstract:
In this issue of Blood Cancer Discovery, Frenking and colleagues demonstrate the prognostic potential of three risk score models to predict hematotoxicity, infections, response rates, and survival following bispecific T-cell engager (TCE) therapy in multiple myeloma. These risk score models, which the authors validated using retrospective real-world data from 278 patients, can easily be calculated using routine blood testing and offer the potential to improve the efficacy and safety of TCE therapy. See related article by Frenking et al., p. 479.
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