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Updated: Mar 13, 2026

A Three-Dimensional Spheroid Model to Investigate the Tumor-Stromal Interaction in Hepatocellular Carcinoma
Published on: September 30, 2021
Abstract:
A massive study spanning 185 countries concludes that about four in 10 cancer cases are linked to modifiable risk factors such as smoking, infections, and alcohol consumption. Stratifying by sex, researchers found three in 10 cancer cases in women and one in two in men were due to modifiable risk factors. The findings "reinforce the call for effective cancer prevention," the researchers say.
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When the function of certain critical genes, especially those involved in cell cycle regulation and cell growth signaling cascades, gets disrupted, it upsets the cell cycle progression. Such cells with unchecked cell cycles start proliferating uncontrollably and eventually develop into tumors.
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