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Related Concept Videos

Epilepsy and Seizures: Overview01:24

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Epilepsy is a chronic neurological disease marked by recurrent, unpredictable seizures. These seizures are caused by abnormal electrical discharges in the brain, leading to behavior, sensation, or consciousness alterations. They can also cause transient impairment of awareness, interfering with daily activities.
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Related Experiment Video

Updated: May 5, 2026

Stereo-Electro-Encephalo-Graphy SEEG With Robotic Assistance in the Presurgical Evaluation of Medical Refractory Epilepsy: A Technical Note
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Stereo-Electro-Encephalo-Graphy SEEG With Robotic Assistance in the Presurgical Evaluation of Medical Refractory Epilepsy: A Technical Note

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Surgical Interventions for Super-Refractory Status Epilepticus: A Systematic Review.

Derrick Barnagian1, Emily In2, Yajing Xiong1

  • 1Department of Neurology, Northwestern University, Evanston, USA.

Neurocritical Care
|March 12, 2026
PubMed
Summary

Super-refractory status epilepticus (SRSE) is a severe neurological condition. Surgical interventions offer a promising treatment, with early intervention significantly improving outcomes and seizure freedom for patients.

Keywords:
Operative surgical proceduresRefractory epilepsyStatus epilepticus

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Last Updated: May 5, 2026

Stereo-Electro-Encephalo-Graphy SEEG With Robotic Assistance in the Presurgical Evaluation of Medical Refractory Epilepsy: A Technical Note
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Area of Science:

  • Neurology
  • Neurosurgery
  • Critical Care Medicine

Background:

  • Super-refractory status epilepticus (SRSE) is a life-threatening neurological emergency.
  • SRSE is defined as status epilepticus lasting over 24 hours despite anesthetic management.
  • Limited contemporary literature exists on effective SRSE treatments.

Conclusions:

  • Surgical interventions are effective for SRSE, including cases with autoimmune and genetic etiologies.
  • Early neurosurgical intervention is associated with improved SRSE resolution and long-term seizure control.
  • Neurosurgery should be considered a viable treatment option for refractory epilepsy cases.