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Updated: May 5, 2026
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Stereo-Electro-Encephalo-Graphy SEEG With Robotic Assistance in the Presurgical Evaluation of Medical Refractory Epilepsy: A Technical Note
Published on: June 13, 2016
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Surgical Interventions for Super-Refractory Status Epilepticus: A Systematic Review
Derrick Barnagian1, Emily In2, Yajing Xiong1
1Department of Neurology, Northwestern University, Evanston, USA.
Neurocritical Care
|March 12, 2026
Summary
Super-refractory status epilepticus (SRSE) is a severe neurological condition. Surgical interventions offer a promising treatment, with early intervention significantly improving outcomes and seizure freedom for patients.
Area of Science:
- Neurology
- Neurosurgery
- Critical Care Medicine
Background:
- Super-refractory status epilepticus (SRSE) is a life-threatening neurological emergency.
- SRSE is defined as status epilepticus lasting over 24 hours despite anesthetic management.
- Limited contemporary literature exists on effective SRSE treatments.
Conclusions:
- Surgical interventions are effective for SRSE, including cases with autoimmune and genetic etiologies.
- Early neurosurgical intervention is associated with improved SRSE resolution and long-term seizure control.
- Neurosurgery should be considered a viable treatment option for refractory epilepsy cases.
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