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Autoimmune Hepatitis and Pregnancy: A Case Report.
Sayali Tulpule1, Vinit Shah2, Chaitanya Ganapule3
1Consultant Physician, Department of Medicine, Poona Hospital & Research Centre, Pune, Maharashtra, India.
The Journal of the Association of Physicians of India
|March 12, 2026
Summary
Autoimmune hepatitis (AIH) in pregnancy requires prompt diagnosis and management. Early identification and care are crucial for successful maternal and fetal outcomes in women with this chronic liver disease.
Area of Science:
- Hepatology
- Immunology
- Obstetrics
Background:
- Autoimmune hepatitis (AIH) is a chronic liver disease causing inflammation and necrosis.
- AIH can progress to fibrosis, cirrhosis, and liver failure.
- The condition disproportionately affects young to middle-aged women and can exacerbate during pregnancy.
Purpose of the Study:
- To raise awareness among healthcare professionals regarding AIH in pregnancy.
- To highlight the importance of timely diagnosis and management for improved maternal and embryonic outcomes.
- To present a case report of AIH diagnosed during early gestation.
Main Methods:
- Case report presentation.
- Review of relevant literature on AIH in pregnancy.
- Clinical case analysis of a primigravida diagnosed at 14 weeks gestation.
Main Results:
- The case report details a primigravida diagnosed with AIH at 14 weeks of pregnancy.
- The report underscores the potential for AIH to cause significant maternal and embryonic complications.
- Successful management strategies are implied for positive outcomes.
Conclusions:
- Autoimmune hepatitis is a critical consideration in pregnant women, especially those presenting with liver abnormalities.
- Early diagnosis and multidisciplinary management are essential for optimizing maternal and fetal health.
- Increased awareness can lead to better patient care and outcomes for AIH during gestation.
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