Studies on prevalence of Hantavirus in small mammals in Southeast Asia: A systematic review and meta-analysis
Zixiao Guo1,2, Hongxin Pan1, Nini Wang1,2
1School of Public Health, Hainan Medical University, Haikou, Hainan, China.
Background:
This study systematically analyzed the prevalence of Hantavirus (HVs) in small mammals across Southeast Asia to evaluate the risks of this zoonotic disease.
Methods:
We searched the Web of Science, PubMed, Embase, Scopus, and Cochrane Library for studies published up to 6 February 2025, extracted data from 28 eligible studies.
Results:
Meta-analysis revealed a pooled prevalence of HVs was 6.07% (986/11,806) in small mammals in Southeast Asia, with the highest prevalence in Indonesia (17.49%) and Singapore (10.53%). The prevalence was higher in samples detected by Enzyme-Linked Immunosorbent Assay (10.68%) and in rodents (8.07%).
Conclusions:
The results of our study highlight the urgency of strengthening surveillance in trade networks with Southeast Asia, particularly in high-risk areas such as Indonesia and Singapore, to mitigate the threat of imported zoonotic diseases.
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