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Mismatch Repair

Mismatch Repair

Organisms are capable of detecting and fixing nucleotide mismatches that occur during DNA replication. This sophisticated process requires identifying the new strand and replacing the erroneous bases with correct nucleotides. Mismatch repair is coordinated by many proteins in both prokaryotes and eukaryotes.
The Mutator Protein Family Plays a Key Role in DNA Mismatch Repair
The human genome has more than 3 billion base pairs of DNA per cell. Prior to cell division, that vast amount of genetic...

Mismatch Repair

Mismatch Repair

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Related Experiment Video

Updated: Mar 14, 2026

Deficient Pms2, ERCC1, Ku86, CcOI in Field Defects During Progression to Colon Cancer

Deficient Pms2, ERCC1, Ku86, CcOI in Field Defects During Progression to Colon Cancer

Published on: July 28, 2010

Immune Checkpoint Blockade in Deficient Mismatch Repair/Microsatellite Instability-High Gastric Cancer: Solid

Guoliang Zheng¹, Xin Zhang¹, Jing Zhang¹

¹Guoliang Zheng, MD, Department of Gastric Surgery, Cancer Hospital of China Medical University, Cancer Hospital of Dalian University of Technology, Liaoning Cancer Hospital & Institute, Shenyang, China, Xin Zhang, MD, Department of Nuclear Medicine, Shengjing Hospital of China Medical University, Shenyang, China, Jing Zhang, MD, School of Pharmacy, China Medical University, Shenyang, China, Zhendong Zheng, MD, Oncology Department, General Hospital of Northern Theater Command, Shenyang, China, Yan Zhao, MD, Department of Gastric Surgery, Cancer Hospital of China Medical University; Cancer Hospital of Dalian University of Technology; Liaoning Cancer Hospital & Institute, Shenyang, China.

Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology

|March 12, 2026

Summary

No abstract available in PubMed .

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