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Hyaluronic Acid Filler for Clavicular Definition: A Novel Cannula Approach
Kyu-Ho Yi1, Isabella Rosellini2, Han Ah Reum Song3
1Division in Anatomy and Developmental Biology, Department of Oral Biology, Human Identification Research Institute, BK21 FOUR Project, Yonsei University College of Dentistry, 50-1 Yonsei-ro, Seodaemun-gu, Seoul, Korea.
The Journal of Craniofacial Surgery
|March 12, 2026
Summary
Hyaluronic acid (HA) fillers offer a safe, minimally invasive method for clavicular enhancement, improving skeletal definition. This technique provides satisfactory, predictable results with minimal side effects, presenting a viable alternative to surgical procedures.
Area of Science:
- Aesthetic Medicine
- Dermatology
- Plastic Surgery
Background:
- Clavicular enhancement with hyaluronic acid (HA) fillers is a novel aesthetic procedure for skeletal definition.
- Advances in filler rheology and subperiosteal placement enhance safety, reversibility, and stability.
Purpose of the Study:
- Review evidence and clinical experience of non-surgical clavicular enhancement using HA fillers (e.p.t.q.® S 500).
- Emphasize anatomical considerations, technical strategies, and patient outcomes.
Main Methods:
- Evaluation of clinical observations and literature on subperiosteal HA filler placement for clavicular contouring.
- Review of imaging validation and reports on durability, biocompatibility, and safety.
Main Results:
- Consistent skeletal definition and high patient satisfaction achieved with HA filler clavicular contouring.
- Rapid recovery with minimal downtime and infrequent, mild, transient adverse events.
Conclusions:
- HA filler treatment of the clavicle is a safe, customizable, and reversible alternative to surgery.
- Detailed anatomical understanding and meticulous technique yield natural, predictable results, expanding injectable body contouring options.

