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Angiectatic sinonasal polyps: A clinicopathological analysis of 20 cases
Chaithra Gowthuvalli Venkataramana1, Murali Mohan Rama Krishna Reddy1, Prayag Rai N1
1Department of Pathology, Kasturba Medical College Mangalore, Manipal Academy of Higher Education, Manipal, India.
Annals of Diagnostic Pathology
|March 12, 2026
Summary
Angiectatic sinonasal polyps (ANPs) are rare but challenging to diagnose, often mimicking tumors. This study highlights their unique features, confirming surgical excision leads to excellent outcomes with no recurrences.
Area of Science:
- Pathology
- Otolaryngology
- Surgical Oncology
Background:
- Angiectatic sinonasal polyps (ANPs) are rare sinonasal pathologies that can be misdiagnosed as neoplasms.
- Their potential for complications necessitates thorough investigation and accurate diagnosis.
Purpose of the Study:
- To explore the clinicopathological characteristics of ANPs.
- To emphasize diagnostic challenges and identify key features for accurate identification.
Main Methods:
- Retrospective analysis of 189 sinonasal polyps over 8 years.
- Evaluation of radiological and histopathological findings.
- Clinical follow-up post-surgical excision.
Main Results:
- 20 cases (10.6%) identified as ANPs, predominantly in males >30 years.
- Common symptoms include nasal obstruction, rhinorrhea, bleeding on touch, and rapid growth.
- Histopathology revealed characteristic vascular proliferation, stromal edema, and atypical fibroblasts.
Conclusions:
- ANPs present diagnostic challenges due to features mimicking malignancy.
- Distinctive histopathological findings aid in diagnosis.
- Surgical excision results in excellent prognosis with no observed recurrences.
