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High-Efficiency Transduction of Liver Cancer Cells by Recombinant Adeno-Associated Virus Serotype 3 Vectors
Published on: March 22, 2011
A sticky situation: E. bolteae adhesion fuels liver cancer
1Institute of Health and Medicine, Hefei Comprehensive National Science Center, Hefei, Anhui, 230601, China; Department of Pharmacy, Center for Xin'an Medicine and Modernization of Traditional Chinese Medicine of IHM, Anhui University of Chinese Medicine, Hefei, Anhui, 230012, China.
None:
Microbial translocation via the gut-liver axis fuel hepatocarcinogenesis primarily through circulating microbial metabolites and molecular patterns. In this issue of Cell Host & Microbe, Ren et al. demonstrate that the liver bacteria Enterocloster bolteae can translocate and directly colonize tumors via a bacterium-host adhesion PbpT-DSG1-MAPK axis to drive tumor progression.

