[Recent advances in hepatic arterial infusion chemotherapy for conversion therapy of hepatocellular carcinoma]

Hepatocellular carcinoma(HCC) is one of the common malignant tumors in China. Most patients are diagnosed at an intermediate or advanced stage, thereby losing the opportunity for curative treatment. This article systematically reviewed the clinical significance, combination strategies, and comparisons with other approaches of hepatic arterial infusion chemotherapy (HAIC) in the conversion therapy of HCC. It highlighted the significant efficacy of HAIC, particularly for patients with massive tumor or those accompanied by vascular tumor thrombus, and emphasized that combination therapies could further enhance the conversion success rate. This review summarized recent advances in HAIC, provided valuable references for clinical practice, and held important implications for improving the prognosis of patients with advanced HCC.