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Clinical Challenges in Transition to Adult Care for Young People With Endocrinopathies

Margaret Zacharin1,2, Quynh-Nhu Nguyen3,4,5

  • 1Department of Endocrinology and Diabetes, Royal Children's Hospital, Parkille, Victoria, Australia.

Clinical Endocrinology
|March 12, 2026
PubMed

Insights

Transitioning pediatric patients with endocrine disorders to adult care requires specialized guidance. This paper provides practical strategies for managing childhood-onset endocrine conditions during this critical phase.

Area of Science:

  • Pediatric Endocrinology
  • Adult Endocrinology
  • Healthcare Transition

Background:

  • Transitioning pediatric patients to adult care is complex.
  • Existing literature lacks practical guidance for managing specific medical aspects.
  • Childhood-onset endocrine disorders often have genetic/epigenetic origins.

Purpose of the Study:

  • Address knowledge gaps in pediatric to adult endocrine care transition.
  • Provide guidance for managing childhood-onset endocrine disorders.
  • Offer strategies for both pediatric and adult clinicians.

Main Methods:

  • Literature review on pediatric to adult endocrine transition.
  • Analysis of management strategies for specific endocrine conditions.
  • Identification of knowledge gaps for adult endocrinologists.

Main Results:

  • Lack of accessible practical guidance for endocrine care transition.
  • Adult endocrinologists may lack familiarity with pediatric endocrine conditions.
  • Specific management strategies for childhood-onset endocrine disorders are needed.

Conclusions:

  • Guidance is essential for effective transition of pediatric endocrine patients.
  • Multidisciplinary approach is crucial for managing endocrine disorders.
  • Highlighting unfamiliar areas in adult practice will improve patient outcomes.

Keywords:
childhood endocrinopathychronic diseasecongenital adrenal hyperplasiahypogonadismhypopituitarismtransition

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