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Farnesyltransferase inhibitor LB42708 disables oncogenic RAS signaling and overcomes gefitinib resistance in NSCLC

Guancong Luo1, Dexuan Li1, Jun Peng2,3

  • 1Center for Pharmaceutical Sciences and Engineering, Faculty of Life Science and Technology, Kunming University of Science and Technology, Kunming, 650500, China.

Cell Communication and Signaling : CCS
|March 13, 2026
PubMed
Abstract

No abstract available in PubMed .

Keywords:
AZD5363Combination therapyEGFR-TKIs resistanceFarnesyltransferaseLB42708NSCLCRAS

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