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C3a and C5a plasma concentrations in patients with diabetic retinopathy: a cross-sectional study

Paula Basso Dias1,2, Iara Messias-Reason1, Germano Ramos Boff2

  • 1Internal Medicine Post Graduate, Clinical Hospital, Federal University of Paraná, Curitiba, Brazil.

International Journal of Retina and Vitreous
|March 13, 2026
PubMed
Abstract

No abstract available in PubMed .

Keywords:
AnaphylatoxinsC3aC5aComplement systemDiabetic retinopathy

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Diabetic Retinopathy01:27

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DefinitionDiabetic retinopathy is a microvascular complication of diabetes affecting the retinal blood vessels.Risk FactorsDiabetic retinopathy is present in almost all individuals with type 1 diabetes and more than 60% of those with type 2 diabetes after two decades of disease.The risk increases with poor glycemic control, hypertension, dyslipidemia, smoking, pregnancy, and puberty.Although cataracts and glaucoma are also more frequent in people with diabetes, retinopathy remains the leading...