Visual analysis of the research hotspots in neoadjuvant therapy for patients with gastric cancer

Tianxing Chen1,2, Yating Liu1,2, Jing Gao2

  • 1Lanzhou University Second School of Clinical Medicine, Lanzhou, Gansu, China.

Abstract

Insights

Research on neoadjuvant therapy for gastric cancer (GC) is rapidly expanding. Key areas include clinical trials, immunotherapy, microsatellite instability, and peritoneal metastasis, indicating significant growth in this field.

Area of Science:

  • Oncology
  • Medical Research
  • Bibliometrics

Background:

  • Gastric cancer (GC) remains a significant global health challenge.
  • Neoadjuvant therapy is crucial for improving GC patient outcomes.
  • Understanding research trends is vital for advancing GC treatment.

Purpose of the Study:

  • To analyze bibliometric data on neoadjuvant therapy for GC.
  • To identify current research hotspots and emerging frontiers.
  • To map the developmental trends in GC neoadjuvant therapy research.

Main Methods:

  • Systematic literature retrieval (1991-2021).
  • Bibliometric analysis using CiteSpace and VOS-viewer software.
  • Identification of research hotspots, frontiers, and trends.

Main Results:

  • A consistent upward trend in publications on neoadjuvant therapy for GC.
  • Current focus on clinical trials and applications of neoadjuvant therapies.
  • Emerging research frontiers include microsatellite instability, peritoneal metastasis, randomized controlled trials, multicenter studies, and regression analysis.

Conclusions:

  • Growing researcher interest and attention in neoadjuvant therapy for GC.
  • Explosive growth in literature concerning neoadjuvant therapy and immunotherapy for GC in the last five years.
  • The current period is critical for the development of neoadjuvant therapy for gastric cancer.

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