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Gene Regulation and Targeted Therapy in Gastric Cancer Peritoneal Metastasis: Radiological Findings from Dual Energy CT and PET/CT
Published on: January 22, 2018
Visual analysis of the research hotspots in neoadjuvant therapy for patients with gastric cancer
Tianxing Chen1,2, Yating Liu1,2, Jing Gao2
1Lanzhou University Second School of Clinical Medicine, Lanzhou, Gansu, China.
Objective:
This study aimed to analyze the research hotspots and frontiers in the field of neoadjuvant therapy for patients with gastric cancer (GC) using bibliometric and identify its developmental trends.
Methods:
The literature related to neoadjuvant therapy for GC systematically retrieved between 1991 and 2021. Bibliometric methods were used to analysis the research hotspots and trends by CiteSpace and VOS-viewer software.
Results:
The number of studies related to neoadjuvant therapies for GC showed an upward trend. Moreover, the current research directions were mostly focused on the clinical trials and applications of neoadjuvant therapies for GC. The frontier research directions included microsatellite instability, peritoneal metastasis, randomized controlled trials, multicenter studies, and regression analysis.
Conclusions:
The interest and attention of researchers in this field are still growing. In the past five years, the literature related to neoadjuvant therapy and immunotherapy for gastric cancer has exploded. It is still an important period and a key stage for the development of neoadjuvant therapy for gastric cancer.
Insights
Research on neoadjuvant therapy for gastric cancer (GC) is rapidly expanding. Key areas include clinical trials, immunotherapy, microsatellite instability, and peritoneal metastasis, indicating significant growth in this field.
Area of Science:
- Oncology
- Medical Research
- Bibliometrics
Background:
- Gastric cancer (GC) remains a significant global health challenge.
- Neoadjuvant therapy is crucial for improving GC patient outcomes.
- Understanding research trends is vital for advancing GC treatment.
Purpose of the Study:
- To analyze bibliometric data on neoadjuvant therapy for GC.
- To identify current research hotspots and emerging frontiers.
- To map the developmental trends in GC neoadjuvant therapy research.
Main Methods:
- Systematic literature retrieval (1991-2021).
- Bibliometric analysis using CiteSpace and VOS-viewer software.
- Identification of research hotspots, frontiers, and trends.
Main Results:
- A consistent upward trend in publications on neoadjuvant therapy for GC.
- Current focus on clinical trials and applications of neoadjuvant therapies.
- Emerging research frontiers include microsatellite instability, peritoneal metastasis, randomized controlled trials, multicenter studies, and regression analysis.
Conclusions:
- Growing researcher interest and attention in neoadjuvant therapy for GC.
- Explosive growth in literature concerning neoadjuvant therapy and immunotherapy for GC in the last five years.
- The current period is critical for the development of neoadjuvant therapy for gastric cancer.

