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Updated: Jul 20, 2026

Pressure Controlled Ventilation to Induce Acute Lung Injury in Mice
Published on: May 5, 2011
Mechanical ventilation in a case of anticoagulant rodenticide toxicity: a case report
Diana Carter1, Carl J Southern1
1University of Florida College of Veterinary Medicine, Gainesville, FL, United States.
Abstract:
A 2.5-year-old male neutered Golden Retriever was taken to an academic teaching hospital in respiratory distress. The patient was intubated, and diagnostics were performed, which found delayed clotting times and evidence of hemorrhage in both his trachea and lungs. The owner mentioned the possibility of anticoagulant rodenticide exposure. Due to upper and lower airway impairment, the patient was mechanically ventilated for more than 24 h while standard treatment was initiated. The patient was able to breathe on his own after 24 h and was discharged home 4 days later. This report documents a dog that required mechanical ventilation due to suspected intramural tracheal membranous hemorrhage and atypical presentation of upper and lower airway hemorrhage caused by vitamin K antagonist rodenticide.

