Related Experiment Video

Updated: Mar 14, 2026

Tubal Cytology of the Fallopian Tube as a Promising Tool for Ovarian Cancer Early Detection

Tubal Cytology of the Fallopian Tube as a Promising Tool for Ovarian Cancer Early Detection

Published on: July 25, 2017

Ovarian Tuberculosis Mimicking Ovarian Malignancy: A Diagnostic Challenge in an Endemic Setting

María E Galaviz Valdez¹, Paula M Cuéllar Pinzón¹, Deborah L Núñez¹

¹Internal Medicine, Hospital Universitario Dr. José Eleuterio González, Monterrey, MEX.

|March 13, 2026

Abstract:

Ovarian tuberculosis is a rare manifestation of extrapulmonary tuberculosis and may closely resemble advanced ovarian carcinoma due to overlapping clinical, biochemical, and radiological features. We report the case of an 18-year-old female who presented with progressive abdominal distension, severe hypogastric pain, and unintentional weight loss. Imaging revealed a left adnexal mass with ascites and retroperitoneal lymphadenopathy suggestive of stage IIIC ovarian carcinoma. Serum CA-125 was markedly elevated (637.4 U/mL). Prior to initiation of chemotherapy, an image-guided TRUCUT biopsy demonstrated chronic granulomatous inflammation with acid-fast bacilli. Ziehl-Neelsen staining was positive, QuantiFERON-TB Gold assay was positive, and culture of the adnexal lesion confirmed Mycobacterium tuberculosis. The patient was treated with first-line anti-tuberculous therapy and showed clinical and radiological improvement. This case highlights the importance of considering tuberculosis in the differential diagnosis of adnexal masses with elevated CA-125, particularly in endemic regions, and emphasizes the value of histopathological confirmation to prevent misdiagnosis and avoid unnecessary oncologic treatment.

Keywords:

adnexal mass ca-125 extrapulmonary tuberculosis female genital tuberculosis ovarian tuberculosis

More Related Videos

An Orthotopic Model of Serous Ovarian Cancer in Immunocompetent Mice for in vivo Tumor Imaging and Monitoring of Tumor Immune Responses

An Orthotopic Model of Serous Ovarian Cancer in Immunocompetent Mice for in vivo Tumor Imaging and Monitoring of Tumor Immune Responses

Published on: November 28, 2010

Murine Model for Non-invasive Imaging to Detect and Monitor Ovarian Cancer Recurrence

Murine Model for Non-invasive Imaging to Detect and Monitor Ovarian Cancer Recurrence

Published on: November 2, 2014

Related Concept Videos

Pulmonary Tuberculosis III

Pulmonary Tuberculosis III

Tuberculosis (TB) is a contagious infection primarily affecting the lung parenchyma but which can also affect other body parts. TB can be classified based on disease development, presentation, and the affected anatomical site.
The first classification is based on the development of the disease, and it includes the following categories:

Oogenesis

Oogenesis

In human women, oogenesis produces one mature egg cell or ovum for every precursor cell that enters meiosis. This process differs in two unique ways from the equivalent procedure of spermatogenesis in males. First, meiotic divisions during oogenesis are asymmetric, meaning that a large oocyte (containing most of the cytoplasm) and minor polar body are produced as a result of meiosis I, and again following meiosis II. Since only oocytes will go on to form embryos if fertilized, this unequal...

Pulmonary Tuberculosis IV

Pulmonary Tuberculosis IV

Tuberculosis, more commonly referred to as TB, is an infectious disease stemming from Mycobacterium tuberculosis. While it primarily impacts the lungs, TB can also affect other body areas. Given its severity and global impact, timely and accurate diagnosis is crucial for controlling its spread and improving patient outcomes.
Several diagnostic approaches are used to detect TB. The conventional method is the Tuberculin Skin Test (TST), also known as the Mantoux test. However, this method has...

Ovaries

Ovaries

The ovaries are roughly the size of almonds and measure approximately 2 to 3 centimeters in length. These paired structures are situated within the pelvic region and are anchored by the mesovarium—a peritoneal extension that also connects them to the wider structure of the broad ligament. The support system extends to the suspensory ligament, housing blood and lymphatic vessels. In addition, the ovarian ligament tethers the ovaries to the uterus.
On the ovarian surface, a layer of...