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Bile Duct Ligation in Mice: Induction of Inflammatory Liver Injury and Fibrosis by Obstructive Cholestasis
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MASH and the race for liver antifibrotics

Quin Wills1

  • 1Ochre Bio, Oxford, United Kingdom.

Frontiers in Gastroenterology (Lausanne, Switzerland)
|March 13, 2026
PubMed
Summary

New metabolic therapies offer hope for treating liver fibrosis in metabolic dysfunction-associated steatohepatitis (MASH). Emerging treatments target liver fat and fibrosis, potentially improving outcomes for patients with chronic liver disease.

Keywords:
antifibroticscombination therapiesliver fibrosismetabolic dysfunction-associated steatohepatitis (MASH)metabolic therapiesprecision medicine

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