Related Experiment Video
Updated: Mar 14, 2026

Closure of a Patent Foramen Ovale PFO: An Intervention Sequence
Published on: December 23, 2022
"Preventing vision loss in pediatric otogenic thrombosis: a case report highlighting surgical interventions"
Fatimah A AlMuhanna1, Wejdan S Hakami1, Abdullah M AlHashem2
1Division of Pediatric Neurology, Department of Pediatrics, Prince Sultan Military Medical City, Riyadh, Saudi Arabia.
Insights
Otogenic cerebral venous sinus thrombosis (CVST) in children, a rare otitis media complication, can cause severe intracranial hypertension. A stepwise approach combining vision-directed and pressure-lowering therapies effectively resolved papilledema and symptoms.
Area of Science:
- Pediatric Neurology
- Ophthalmology
- Infectious Diseases
Background:
- Otogenic cerebral venous sinus thrombosis (CVST) is a rare but serious complication of acute otitis media in children.
- CVST can lead to severe intracranial hypertension, presenting with vision-threatening papilledema.
Abstract:
Otogenic cerebral venous sinus thrombosis (CVST) is a rare complication of acute otitis media in children and may lead to severe intracranial hypertension with vision-threatening papilledema. We report the case of a 4-year-old girl with otogenic CVST involving the left transverse and sigmoid sinuses, complicated by marked intracranial hypertension and bilateral Frisén grade 4 papilledema. Serial ophthalmologic assessments and neuroimaging were performed to evaluate the response to sequential therapeutic interventions. Despite treatment with intravenous antibiotics, anticoagulation, and medical intracranial pressure-lowering therapy, papilledema and symptoms persisted. Optic nerve sheath fenestration (ONSF) resulted in partial improvement; however, subsequent temporary external lumbar drainage led to rapid and sustained resolution of papilledema, headache, and left abducens nerve palsy, with preservation of visual function. This case underscores the importance of a structured, stepwise escalation strategy incorporating both vision-directed and global intracranial pressure-lowering interventions when medical therapy alone is insufficient.
Related Concept Videos
Venous Thrombosis III: Interprofessional Care
Angle Closure Glaucoma: Treatment
Open Angle Glaucoma: Treatment
Drugs such as carbonic anhydrase inhibitors, α2- and...
Glaucoma: Overview
Aneurysm IV: Nursing Management
Mitral Stenosis III: Medical Management

