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Updated: Mar 14, 2026

Endoscopic Vacuum Therapy for the Treatment of Anastomotic Leakage after Total Gastrectomy with Esophagojejunostomy
Published on: August 22, 2025
Endoscopic vacuum therapy in the upper gastrointestinal tract
Kirsten Boonstra1, Lisanne M D Pattynama2,3,4,5, Yasmijn J van Herwaarden1
1Radboud University Medical Center, Department of Gastroenterology and Hepatology, Nijmegen, Netherlands.
Endoscopic vacuum therapy (EVT) offers an effective and safe method for treating upper gastrointestinal defects. This overview guides clinicians on EVT implementation, standardization, and avoiding common practice errors.
Area of Science:
- Gastroenterology
- Endoscopy
- Surgical Innovation
Background:
- Transmural defects in the upper gastrointestinal tract present significant clinical challenges.
- Endoscopic vacuum therapy (EVT) has emerged as a versatile and promising intervention for these defects.
Purpose of the Study:
- To provide a comprehensive overview of Endoscopic Vacuum Therapy (EVT).
- To guide clinicians in the decision-making process for managing upper gastrointestinal defects using EVT.
- To highlight common challenges and potential pitfalls in EVT implementation.
Main Methods:
- Literature review of existing studies and clinical practices related to EVT.
- Analysis of EVT mechanisms, indications, and available devices.
- Compilation of data on EVT efficacy, safety, and complications.
Main Results:
- EVT demonstrates significant efficacy and a favorable safety profile in managing transmural gastrointestinal defects.
- Standardized protocols and evidence-based practices are crucial for optimal EVT outcomes.
- Understanding common challenges is key to successful EVT implementation and avoiding errors.
Conclusions:
- Endoscopic vacuum therapy is a valuable tool for upper gastrointestinal defect management.
- Standardization and adherence to evidence-based practices are essential for maximizing EVT benefits.
- This overview aims to improve clinical decision-making and reduce errors in daily EVT practice.
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