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Updated: Mar 14, 2026

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Role of Endomyocardial Biopsy and Bachmann's Bundle Pacing for Sinus Node Dysfunction in Cardiac Amyloidosis

Koji Sudo1, Kenji Kuroki1, Chisa Asahina1

  • 1Department of Cardiovascular Medicine, University of Yamanashi, Kofu, Japan.

JACC. Case Reports
|March 13, 2026
PubMed

Insights

Bachmann's bundle (BB) pacing is a safe and effective treatment for patients with light-chain cardiac amyloidosis (AL-CA) and sinus node dysfunction (SND). This innovative pacing method improves heart failure outcomes by enhancing cardiac efficiency.

Area of Science:

  • Cardiology
  • Electrophysiology
  • Cardiac Amyloidosis Research

Background:

  • Light-chain cardiac amyloidosis (AL-CA) involves myocardial amyloid deposition.
  • Sinus node dysfunction (SND) is a common complication.
  • Limited evidence exists on Bachmann's bundle (BB) pacing in AL-CA patients with SND.
Abstract

Keywords:
Bachmann's bundle pacingcardiac amyloidosissinus node dysfunction

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