Treatment of Capsular Contracture with Poly-4-Hydroxybutyrate

Capsular contracture is the most frequent complication following breast augmentation, prompting many revision surgeries. Its prevention has evolved through precise surgical technique, antimicrobial measures, and the use of innovative materials. Advances in breast reconstruction-from submuscular and dual-plane to prepectoral placement-have shaped modern contracture management. Acellular dermal matrices and biosynthetic scaffolds like poly-4-hydroxybutyrate (P4HB) have proven effective in reducing contracture rates, with P4HB offering benefits such as lower costs and improved pocket stability. Today, the combination of prepectoral positioning, advanced matrices/scaffolds, and strict antimicrobial protocols allows for consistent and successful prevention and treatment of capsular contracture.