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A Decade of the GSTT Aortic Infection Programme: A Description of a Clinical Management Algorithm by a
Thomas Richards1, Carolyn Hemsley1, Nicholas Price1
1Guy's and St Thomas' NHS Foundation Trust, London SE1 9RT, UK.
Journal of Clinical Medicine
|March 14, 2026
Summary
A dedicated multidisciplinary aortic infection service and standardized algorithm improve patient outcomes for rare mycotic aortic aneurysms and aortic graft infections. This approach ensures consistent decision-making and facilitates data collection for future advancements.
Area of Science:
- Vascular Surgery
- Infectious Diseases
- Healthcare Management
Background:
- Mycotic aortic aneurysm and aortic graft infections are rare, complex pathologies.
- Effective management requires specialized expertise and coordinated care.
- Previous literature lacks comprehensive descriptions of dedicated management strategies.
Purpose of the Study:
- To report on the experience and management strategy of a high-volume, multidisciplinary aortic infection service.
- To demonstrate the impact of a standardized management algorithm on decision-making and patient outcomes.
- To highlight the benefits of a centralized, multidisciplinary approach for complex aortic pathologies.
Main Methods:
- Development and examination of a multidisciplinary service for aortic infections.
- Standardization of management protocols and decision-making processes.
- Analysis of service impact on patient outcomes and data collection.
Main Results:
- The specialized service and algorithm led to improved patient outcomes.
- Standardized management facilitated timely and consistent decision-making.
- The multidisciplinary approach enabled prospective data collection and analysis.
Conclusions:
- A comprehensive management algorithm for mycotic aortic aneurysm and aortic graft infection has been successfully implemented.
- A dedicated, multidisciplinary specialist service utilizing a standardized algorithm delivers superior patient outcomes.
- This model provides a framework for managing complex aortic infections and adapting to future evidence.
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