Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Confocal Fluorescence Microscopy01:16

Confocal Fluorescence Microscopy

Confocal microscopy is an advanced microscopic technique. The prime advantage of the confocal microscope over other microscopy techniques is its ability to block the out-of-focus light from the illuminated samples using pinholes. It is widely used with fluorescence optics to obtain high-resolution, sharp contrast images. Unlike optical microscopes, confocal microscopes use a focused beam of light laser to scan the entire sample surface at different z-planes. These microscopes are, therefore,...
Super-resolution Fluorescence Microscopy01:37

Super-resolution Fluorescence Microscopy

Super-resolution fluorescence microscopy (SRFM) provides a better resolution than conventional fluorescence microscopy by reducing the point spread function (PSF). PSF is the light intensity distribution from a point that causes it to appear blurred. Due to PSF, each fluorescing point appears bigger than its actual size, and it is the PSF interference of nearby fluorophores that causes the blurred image. Various approaches to achieving higher resolution through SRFM have recently been developed.

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Cellulose-Based Hydrogels for Chronic Wound Healing: Bridging Biomaterial Design and Clinical Unmet Needs.

Gels (Basel, Switzerland)·2026
Same author

Stimuli-Responsive Nanomaterial-Based Biosensor Structures for Wound Care: pH, ROS, and Temperature Sensing Strategies.

Micromachines·2026
Same author

Mechanism, Efficacy, and Safety of Natural Antibiotics.

Antibiotics (Basel, Switzerland)·2025
Same author

Laser-Based Fabrication of Hydrogel Scaffolds for Medicine: From Principles to Clinical Applications.

Gels (Basel, Switzerland)·2025
Same author

Sustainable Hydrogels in Water Treatment-A Short Review.

Gels (Basel, Switzerland)·2025
Same author

Polymeric Composite Thin Films Deposited by Laser Techniques for Antimicrobial Applications-A Short Overview.

Polymers·2025

Related Experiment Video

Updated: Jun 27, 2026

Fabrication of Ultra-thin Color Films with Highly Absorbing Media Using Oblique Angle Deposition
06:30

Fabrication of Ultra-thin Color Films with Highly Absorbing Media Using Oblique Angle Deposition

Published on: August 29, 2017

8.8K

Biocompatible Thin Films Deposited by Laser Techniques.

Andrei Teodor Matei1, Anita Ioana Visan2

  • 1IT Center for Science and Technology, 011702 Bucharest, Romania.

Materials (Basel, Switzerland)
|March 14, 2026
PubMed
Summary

Biocompatible thin films are crucial for medical devices. This review compares laser-based deposition methods with alternatives like PVD and CVD, guiding selection for advanced biomedical applications.

Keywords:
biocompatible thin filmsfilm stoichiometryimplantable deviceslaser depositionsurface engineering

More Related Videos

Procedure for the Transfer of Polymer Films Onto Porous Substrates with Minimized Defects
05:02

Procedure for the Transfer of Polymer Films Onto Porous Substrates with Minimized Defects

Published on: June 22, 2019

7.2K
Author Spotlight: Advancements in High-Performance Thermoelectric Thin Films Through Radio Frequency Magnetron Sputtering
04:22

Author Spotlight: Advancements in High-Performance Thermoelectric Thin Films Through Radio Frequency Magnetron Sputtering

Published on: May 17, 2024

3.9K

Related Experiment Videos

Last Updated: Jun 27, 2026

Fabrication of Ultra-thin Color Films with Highly Absorbing Media Using Oblique Angle Deposition
06:30

Fabrication of Ultra-thin Color Films with Highly Absorbing Media Using Oblique Angle Deposition

Published on: August 29, 2017

8.8K
Procedure for the Transfer of Polymer Films Onto Porous Substrates with Minimized Defects
05:02

Procedure for the Transfer of Polymer Films Onto Porous Substrates with Minimized Defects

Published on: June 22, 2019

7.2K
Author Spotlight: Advancements in High-Performance Thermoelectric Thin Films Through Radio Frequency Magnetron Sputtering
04:22

Author Spotlight: Advancements in High-Performance Thermoelectric Thin Films Through Radio Frequency Magnetron Sputtering

Published on: May 17, 2024

3.9K

Area of Science:

  • Biomaterials Science
  • Surface Engineering
  • Medical Device Technology

Background:

  • Biocompatible thin films are vital for medical device integration, longevity, and reducing complications.
  • Diverse deposition techniques exist, each with unique advantages for tailoring surface properties without altering bulk characteristics.
  • Laser-based methods (PLD, MAPLE), PVD, CVD, and others offer distinct capabilities for fabricating biomedical films.

Purpose of the Study:

  • To comprehensively compare laser-based thin-film deposition techniques with alternative methods.
  • To provide critical insights into the strengths, limitations, and suitability of various deposition strategies for biomedical applications.
  • To guide researchers and clinicians in selecting optimal thin-film deposition methods for next-generation biomedical devices.

Main Methods:

  • Review and comparison of established and emerging thin-film deposition techniques.
  • Analysis of methods including Pulsed Laser Deposition (PLD), Matrix-Assisted Pulsed Laser Evaporation (MAPLE), Physical Vapor Deposition (PVD), Chemical Vapor Deposition (CVD), and others.
  • Evaluation of techniques based on precision, stoichiometry preservation, temperature requirements, coating uniformity, conformality, and chemical control.

Main Results:

  • Laser-based methods offer precision and stoichiometry control, suitable for low-temperature processing.
  • PVD techniques provide uniform, adherent coatings with controlled thickness and composition.
  • CVD/PECVD enable conformal coatings with excellent chemical control, ideal for polymers and ceramics.

Conclusions:

  • No single deposition technique is universally optimal; selection depends on specific clinical application requirements.
  • Ongoing challenges include optimizing film properties, ensuring reproducibility, and scaling up production.
  • This review synthesizes current knowledge to aid informed decision-making in biomedical thin-film fabrication.