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Drugs, encompassing various chemical compounds from natural sources, lab synthesis, or genetic engineering, elicit different biological responses in living organisms. Some of these responses are desirable or therapeutic, while others are undesirable. The primary goal of administering a drug is to achieve a therapeutic effect, that is, to address a specific disease or health condition. Any concurrent effects outside of this therapeutic outcome are considered undesirable. These undesirable...
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Toxicity tests in animals are grounded on two main assumptions: first, the effects observed in laboratory animals can be extrapolated to humans, especially when adjusted for body surface area; second, high-dose exposure in animals is essential to identify potential human hazards from lower doses. This is based on the quantal dose-response concept, which faces the challenge of extrapolating results from relatively few test animals to much larger human populations. For example, a 0.01% incidence...
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Updated: Mar 15, 2026

Extraction and Purification of Polyphenols from Freeze-dried Berry Powder for the Treatment of Vascular Smooth Muscle Cells In Vitro
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Effects of Plant Extracts on Human Health-2nd Edition.

Fátima Regina Mena Barreto Silva1, Marcela Aragón Novoa1,2

  • 1Instituto de Bioeletricidade Celular (IBIOCEL): Ciência & Saúde, Departamento de Bioquímica, Universidade Federal de Santa Catarina, Florianópolis 88049-900, SC, Brazil.

Nutrients
|March 14, 2026
PubMed
Summary

Plant extracts contain bioactive compounds with potential health benefits. Further research explores their chemical makeup and therapeutic applications for human well-being.

Area of Science:

  • Phytochemistry and Pharmacology
  • Natural Product Chemistry

Background:

  • Plant extracts are increasingly studied for their health impacts.
  • Their diverse chemical profiles offer therapeutic potential.

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