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Related Concept Videos

Parenteral Drug Delivery Systems: Injectables, Implants, and Infusion Devices01:28

Parenteral Drug Delivery Systems: Injectables, Implants, and Infusion Devices

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Parenteral drug delivery systems play a crucial role in modern therapeutics by enabling the direct administration of drugs into the systemic circulation, bypassing the gastrointestinal tract. These systems are particularly valuable for poorly absorbed oral medications that are unstable in the digestive environment or require rapid onset or sustained therapeutic levels. Delivery is achieved through intravenous, intramuscular, or subcutaneous routes, each selected based on the drug's properties...
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Drug Delivery Systems: Different Types01:27

Drug Delivery Systems: Different Types

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Conventional oral drug products, termed immediate-release (IR) formulations, are engineered to promptly release their active pharmaceutical ingredient (API) upon ingestion, typically in tablets or capsules. This rapid release often results in swift drug absorption and consequent pharmacodynamic effects, although the timing and intensity can vary depending on the drug's properties. Prodrugs within these formulations require metabolic conversion to activate their pharmacodynamic effects,...
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Intrauterine Drug Delivery Systems01:21

Intrauterine Drug Delivery Systems

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Controlled-release systems for intravaginal and intrauterine drug delivery have been developed primarily for the administration of contraceptive steroid hormones. These delivery routes circumvent first-pass hepatic metabolism, thereby enhancing bioavailability and allowing for reduced systemic dosages compared to oral administration. Such approaches contribute to improved therapeutic efficacy and patient compliance, particularly in long-term contraceptive regimens.Intravaginal Drug Delivery...
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Transdermal Drug Delivery Systems01:18

Transdermal Drug Delivery Systems

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Transdermal drug delivery systems (TDDS) enable the controlled release of drugs across the skin into systemic circulation. They are particularly advantageous for drugs with short half-lives or narrow therapeutic indices, as they maintain consistent plasma concentrations and reduce the risk of subtherapeutic or toxic levels.TDDS are categorized into monolithic, reservoir, and mixed systems. Monolithic systems embed the drug in a polymer matrix, where diffusion governs release. Reservoir systems...
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Modified-Release Drug Delivery Systems: Stimuli-Activated01:30

Modified-Release Drug Delivery Systems: Stimuli-Activated

73
Stimuli-activated drug delivery systems are designed to release drugs in response to specific physical, chemical, or biological stimuli. These systems often utilize hydrogels—three-dimensional, hydrophilic polymer networks capable of swelling in aqueous environments and retaining significant fluid volumes. Upon exposure to particular stimuli, these hydrogels undergo structural transitions that allow the embedded drug to be released. Due to this adaptive behavior, such systems are also...
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Site-Targeted Drug Delivery Systems: Polymeric Carriers01:24

Site-Targeted Drug Delivery Systems: Polymeric Carriers

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Polymeric carriers enhance targeted drug delivery by increasing efficacy while minimizing off-target effects. These carriers comprise a biodegradable polymeric backbone integrated with functional elements that enable targeting, improve physicochemical properties, and regulate drug release.Targeting MechanismsThe targeting ability of polymeric carriers is mediated by a homing device, which is a molecular recognition component designed to selectively bind to specific tissues or cells. Monoclonal...
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Marine-Derived Medical Devices and Therapeutic Delivery Systems.

Paula Isabel Hueso-Jiménez1,2,3, David T Wu4,5,6,7, Chris Hyeongseop Keum1,2,8,9

  • 1Harvard Medical School, Boston, Massachusetts, USA.

Advanced Healthcare Materials
|March 14, 2026
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Summary

Marine biomaterials offer unique properties for medical devices, tissue engineering, and wound healing. Sustainable production and biotechnology integration are key for patient accessibility and circular economy principles.

Keywords:
biomaterialsbiotechnologymarine‐derived productsmedical devicessustainable economy

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Area of Science:

  • Biomaterials Science
  • Marine Biotechnology
  • Regenerative Medicine

Background:

  • Marine-derived products possess unique physical, chemical, and biological properties beneficial for biomedical applications.
  • These properties include mechanical reinforcement, underwater adhesion, swelling capacity, and biocompatibility, supporting cellular functions vital for tissue engineering and wound healing.

Purpose of the Study:

  • To review marine-derived biomaterials and medical devices.
  • To analyze their natural properties and highlight advantages in scaffolds, adhesives, and drug delivery systems.
  • To discuss the potential of marine organisms as sources for advanced biomedical applications.

Main Methods:

  • Literature review of marine organisms including Porifera, Cnidaria, Mollusca, Chordata, Chlorophyta, and Cyanobacteria.
  • Analysis of natural properties of marine-derived products.
  • Evaluation of applications in scaffolds, adhesives, and drug delivery systems.

Main Results:

  • Marine sources provide versatile biomaterials with properties suitable for tissue engineering and wound healing.
  • Scaffolds, adhesives, and drug delivery systems derived from marine organisms show significant promise.
  • Successful clinical translation requires suitable controls and sustainable scale-up processes.

Conclusions:

  • Marine-derived biomaterials represent a promising frontier in medical devices and regenerative medicine.
  • Biotechnology and waste valorization offer pathways for sustainable production and integration into a circular economy.
  • Further research and development are needed to realize the full clinical potential of these marine resources.