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Prioritarianism in gene therapy ethics balances cost-benefit with aiding the worst-off. This paper explores applying Derek Parfit's prioritarianism to gene therapy decisions, proposing a new time-relative approach.

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Area of Science:

  • Bioethics
  • Medical Ethics
  • Health Economics

Background:

  • Gene therapies for severe genetic diseases present significant ethical challenges due to high costs.
  • Decisions on gene therapy provision involve balancing treatment benefits against costs and addressing medical needs.
  • Prioritarianism, focusing on benefiting those who are worse off, is a key ethical consideration.

Purpose of the Study:

  • To explore the application of prioritarianism to gene therapy decision-making.
  • To examine how Derek Parfit's version of prioritarianism can be interpreted and practically applied in medical ethics.
  • To propose and defend a novel "time-relative" version of priority for gene therapy allocation.

Main Methods:

  • Philosophical analysis of prioritarianism, specifically Derek Parfit's account.
  • Ethical assessment of applying prioritarian principles to gene therapy.
  • Development of a new theoretical framework for time-relative priority in medical ethics.

Main Results:

  • Existing ethical frameworks may not fully address the complexities of gene therapy allocation.
  • Parfit's prioritarianism offers a valuable lens but requires careful interpretation for practical medical ethics.
  • A time-relative approach to priority can potentially refine how gene therapy benefits are distributed over time.

Conclusions:

  • Applying prioritarianism to gene therapy requires careful consideration of its impact on future individuals.
  • The proposed time-relative priority offers a nuanced approach to ethical decision-making in gene therapy.
  • Further research is needed to integrate this theoretical framework into clinical practice and health policy.