Effects of Transradial Catheterisation on Radial Artery Bypass Graft Patency: A Systematic Review and Meta-Analysis

Yantong Wang1, Varun Sharma2, Tony Vu3

  • 1School of Translational Medicine, Monash University, Melbourne, Vic, Australia; Department of Surgery, Monash University, Melbourne, Vic, Australia.

PubMed

Insights

Prior transradial catheterisation reduces radial artery bypass graft patency. Surgeons should carefully consider using previously catheterised radial arteries for coronary artery bypass grafting due to increased graft failure risk.

Area of Science:

  • Cardiovascular Surgery
  • Vascular Grafting
  • Interventional Cardiology

Background:

  • Transradial catheterisation is standard for coronary angiography.
  • Radial artery (RA) is a common choice for coronary artery bypass grafting (CABG).
  • Uncertainty exists regarding the suitability of previously catheterised RA (CRA) as a CABG conduit.

Purpose of the Study:

  • To systematically review and meta-analyze the patency of previously catheterised radial artery (CRA) bypass grafts compared to non-catheterised radial artery (NCRA) grafts.

Main Methods:

  • Systematic search of MEDLINE, Embase, and Scopus for comparative studies.
  • Inclusion of four observational studies (400 patients).
  • Random-effects models for pooled effect sizes, heterogeneity assessed by I²; small-study effects examined via funnel plot/Egger's test.

Main Results:

  • CRA graft patency (73.2%) was lower than NCRA (83.9%).
  • Pooled odds of graft failure were significantly higher for CRA (OR 1.82; 95% CI 1.26-2.61; p=0.001).
  • Mean follow-up was approximately 2 years; no significant small-study biases were detected.

Conclusions:

  • Prior transradial catheterisation is linked to reduced radial artery bypass graft patency.
  • Caution is advised when selecting CRA for critical targets in CABG.
  • Further prospective studies are needed to identify risk modifiers.
Abstract

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