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Updated: Mar 16, 2026

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Polymorphisms in IRF3 exon 1 influence the immune response to Brucella infection in small ruminants

U A Rossi1,2, M E Caffaro3, D N Gaute4

  • 1Instituto de Patobiología Veterinaria IPVET, UEDD INTA-CONICET, Nicolás Repetto 2751, Hurlingham, Buenos Aires, B1686, Argentina. rossi.ursula@inta.gob.ar.

Mammalian Genome : Official Journal of the International Mammalian Genome Society
|March 15, 2026
PubMed
Abstract

No abstract available in PubMed .

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The evolution of new genes is critical for speciation. Exon recombination, also known as exon shuffling or domain shuffling, is an important means of new gene formation. It is observed across vertebrates, invertebrates, and in some plants such as potatoes and sunflowers. During exon recombination, exons from the same or different genes recombine and produce new exon-intron combinations, which might evolve into new genes. 
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