Global Trends of Research on Meningococcal Disease in the 21st century

Hongmei Chen1, Jian Li1

  • 1Basic Medical College, Guangzhou University of Chinese Medicine, Guangzhou, China.

PubMed

Insights

Meningococcal disease research has surged since 2000, with the US and Europe leading studies on vaccines and prevention. This analysis maps key research trends for global public health insights.

Area of Science:

  • Public Health
  • Infectious Diseases
  • Epidemiology

Background:

  • Meningococcal disease (MD), caused by Neisseria meningitides (Nm), presents significant global public health challenges due to high morbidity and mortality.
  • Despite over two centuries of study, MD remains a critical area of research and concern worldwide.

Purpose of the Study:

  • To conduct a bibliometric analysis of the evolving research landscape of meningococcal disease.
  • To identify key research trends, leading countries, institutions, and impactful research areas in MD.

Main Methods:

  • Bibliometric analysis using Web of Science (WoS) database indicators.
  • Analysis included publication volume, country, author, affiliation, citations, journals, keywords, and research impact bursts.
  • Visualization tools and keyword co-occurrence analysis were employed.

Main Results:

  • A significant increase in publication volume on MD observed after the year 2000.
  • The United States and European nations (UK, France) are prominent in MD research.
  • Key research focuses include vaccine development, immunization, epidemic prevention, and disease control.

Conclusions:

  • Bibliometric analysis reveals dynamic growth and key focus areas in meningococcal disease research.
  • The findings provide a valuable research map to guide future investigations in MD.
  • Continued focus on vaccines and prevention strategies is evident in the scientific literature.

Related Concept Videos

Microorganisms in Medicine and Therapeutics01:29

Microorganisms in Medicine and Therapeutics

Microorganisms play a fundamental role in vaccine development, gene therapy, and therapeutic production. Their biological properties are harnessed to advance medicine and public health. Beyond immunization, microorganisms contribute to gut health, antibiotic synthesis, and genetic disease treatment.Live Attenuated and Inactivated VaccinesLive attenuated vaccines, such as the measles, mumps, and rubella (MMR) vaccine, utilize weakened forms of pathogens to closely resemble natural infections.
1.3K
History of Microbiology01:28

History of Microbiology

Microbiology, a scientific field dedicated to the study of microorganisms, has undergone profound development since its inception in the 17th century. Its history is marked by key discoveries and technological advancements that have shaped our understanding of life at the microscopic level and transformed medicine, agriculture, and industry.Early Foundations of MicrobiologyThe early foundations of microbiology were built on groundbreaking observations and the development of pioneering...
13.7K
Modern Molecular Taxonomy01:29

Modern Molecular Taxonomy

Advancements in molecular biology have revolutionized the identification and characterization of bacteria, with multiple methods leveraging DNA sequencing for enhanced precision. As sequencing technologies improve and costs decline, these approaches are increasingly used in clinical, environmental, and evolutionary studies.Multilocus Sequence Typing (MLST) examines several housekeeping genes, essential chromosomal genes encoding cellular functions, to distinguish strains. Approximately...
815
Factors Affecting the Risk of Infection01:26

Factors Affecting the Risk of Infection

The hosts' susceptibility to infection depends on several factors. The integrity of the skin and mucous membranes helps protect the body against microbial attacks. When the skin is altered, the chance of infection, limb loss, and even death increases.
The integrity and count of the white blood cells help the body resist pathogens and fight infection. When impaired, it reduces the body's resistance to pathogens. The acidic pH levels of the gastrointestinal, genitourinary tracts, and skin...
14.5K
Development of Antibiotic Resistance01:30

Development of Antibiotic Resistance

Antibiotic resistance is a major public health concern that arises when bacteria evolve mechanisms to withstand the effects of antibiotic treatments. This resistance can be intrinsic, acquired through genetic mutations, or transferred between bacteria via horizontal gene transfer. The development of antibiotic resistance poses significant challenges in treating bacterial infections and necessitates ongoing research to develop new therapeutic strategies.Intrinsic resistance occurs when bacterial...
1.8K