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Updated: Mar 16, 2026

Transcranial Direct Current Stimulation for Online Gamers
Published on: November 9, 2019
Cardiovascular and pulmonary response in gaming disorder: A systematic review protocol
Hela Cherif1, Sabrine Louhaichi2, Soumaya Debiche1
1Internal Security Forces Hospital, Pulmonology Department; Health and environment in Security Forces research laboratory LR211NT01, Tunis; Tunisia, Tunis El Manar University, Faculty of Medicine of Tunis, Tunis; Tunisia.
Introduction:
Internet Gaming Disorder (IGD) is a recognized mental health condition associated with autonomic nervous system (ANS) dysregulation. While heart rate variability (HRV) has been studied, ventilatory responses remain poorly explored. This systematic review aims to evaluate the impact of IGD on cardiovascular (HRV) and pulmonary (respiratory rate) parameters.
Methods:
To conduct this systematic review, a literature search will be conducted on PubMed, Scopus, and Embase. We will include studies assessing HRV and respiratory rate in individuals aged ≥12 years with IGD. Studies without objective ANS measurements or those with non-DSM-5-defined populations will be excluded. Data extraction will focus on HRV (continuous ECG) and respiratory rate variations, stratified by gaming context and IGD severity. The risk of bias will be assessed using ROBINS-I.
Concluson:
This review will clarify ANS dysregulation patterns in IGD, informing clinical monitoring strategies. Limitations may include heterogeneity in measurement methods.
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