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Breaking Barriers: Advancing Transdermal Drug Delivery for Bioactive Compounds.

Sakshi Soni1, Sunny Rathee1,2, Umesh K Patil1

  • 1Department of Pharmaceutical Sciences, Dr. Harisingh GourVishwavidyalaya (A Central University), Sagar, Madhya Pradesh, 470003, India.

Current Pharmaceutical Design
|March 15, 2026
PubMed
Summary

Transdermal drug delivery (TDD) offers improved bioavailability and patient compliance. Innovations like microneedles and nanoformulations enhance TDD efficacy, though challenges like skin irritation remain.

Keywords:
3D printing technologychemicalnaturalpenetration enhancerphysicalskin barrier.

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