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Author Spotlight: Enhancing Coronary Artery Revascularization
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Author Spotlight: Enhancing Coronary Artery Revascularization

Published on: September 15, 2023

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Comparing the Long-term Outcomes of Coronary Artery Bypass Grafting (CABG) vs. Percutaneous Coronary Intervention

Rubela Ray1, Shivam Singla2, Ghazala S Virk3

  • 1Bankura Sammilani Medical College, Bankura, India.

Current Cardiology Reviews
|March 15, 2026
PubMed

Insights

For multivessel coronary artery disease (MVD), Coronary Artery Bypass Grafting (CABG) shows better long-term survival and fewer repeat procedures than Percutaneous Coronary Intervention (PCI). However, CABG has a slightly higher stroke risk, necessitating personalized treatment choices.

Area of Science:

  • Cardiology
  • Interventional Cardiology
  • Cardiac Surgery

Background:

  • Multivessel Coronary Artery Disease (MVD) is commonly treated with Coronary Artery Bypass Grafting (CABG) or Percutaneous Coronary Intervention (PCI).
  • The long-term comparative effectiveness of CABG versus PCI for MVD is not well-established.

Purpose of the Study:

  • To compare the long-term effectiveness of CABG and PCI in patients with MVD.
  • To evaluate outcomes including mortality, repeat revascularization, and stroke.

Main Methods:

  • A systematic review and meta-analysis of randomized and observational studies.
  • Included patients with MVD followed for at least 5 years.
  • Pooled data using random-effects or fixed-effects models based on heterogeneity.

Main Results:

  • Thirteen studies were included in the analysis.
  • CABG was associated with significantly lower all-cause mortality (RR 0.82) and repeat revascularizations (RR 1.98) compared to PCI.
  • A slightly increased risk of stroke was observed after CABG.

Conclusions:

  • CABG demonstrates superior long-term survival and reduced adverse events in MVD patients.
  • The increased stroke risk with CABG necessitates individualized treatment decisions.
  • PCI remains a viable option for patients with lower-risk anatomy or surgical contraindications.
Abstract

Keywords:
Coronary artery bypass grafting (CABG)SYNTAX score.diabetes mellituslong-term outcomesmajor adverse cardiovascular events (MACE)meta-analysismultivessel disease (MVD)percutaneous coronary intervention (PCI)

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