[Use of compounded formulations in dermatologic conditions in a Family and Community Medicine Dermatology Working...

Magistral compounding is a relevant therapeutic tool in dermatology due to its ability to personalize treatments for common dermatoses. The aim of this study was to describe the use of magistral compounding in dermatological conditions among family physicians belonging to the Dermatology Working Group of SEMERGEN and to identify the most frequently treated clinical entities.

An observational, cross-sectional, and descriptive study was conducted using a 30-item online survey addressed to members of the SEMERGEN Dermatology Working Group. Participation was voluntary, anonymous, and unpaid. Sociodemographic variables, frequency of magistral compounding use in 22 dermatological conditions, and recommendations of active cosmetic ingredients were collected. Descriptive analysis was performed using absolute and relative frequencies.

A total of 50 valid surveys were analyzed. Seventy-eight percent of participants were women, and the predominant age group was 30-40 years (52%). Most respondents worked in public primary care (88%) and in urban settings (66%). Magistral compounding was most frequently used for diaper dermatitis (58%), anal fissure (46%), atopic dermatitis of the external auditory canal, and herpetic infections (44%). It was also used in psoriasis, rosacea, and hyperpigmentation disorders (32%). Its use was less frequent in oral mucosal conditions and in diseases with well-established commercial alternatives. All physicians reported recommending anti-aging active ingredients, predominantly via commercial products.

Magistral compounding remains a useful therapeutic option for common dermatoses where treatment personalization provides clinical benefit. Educational and logistical barriers persist, highlighting the need to strengthen specific training and improve coordination with compounding pharmacies.